Modulation of rat incisor odontoblast plasma membrane-associated Ca2+ with nifedipine
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Characterization of Ca2+ fluxes in rat liver plasma-membrane vesicles.
Inside-out plasma-membrane vesicles isolated from rat liver [Prpic, Green, Blackmore & Exton (1984) J. Biol. Chem. 259, 1382-1385] accumulated a substantial amount of 45Ca2+ when they were incubated in a medium whose ionic composition and pH mimicked those of cytosol and which contained MgATP. The Vmax of the initial 45Ca2+ uptake rate was 2.9 +/- 0.6 nmol/min per mg and the Km for Ca2+ was 0.5...
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Development of myometrium in young female rats was stimulated by administration of diethylstilboestrol. Plasma membrane and sarcoplasmic reticulum from rat myometrium were separated by a new and rapid method using a Percoll gradient. Calcium uptake was inhibited in plasma membrane vesicles isolated from oxytocin-treated myometrium, while no consistent effect of oxytocin was found on the Ca2+ up...
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The plasma membrane Ca(2+) ATPase (PMCA) plays a major role in restoring Ca(2+) to basal levels following transient elevation by neuronal activity. Here we examined the effects of various stimuli that increase [Ca(2+)](i) on PMCA-mediated Ca(2+) clearance from hippocampal neurons. We used indo-1-based microfluorimetry in the presence of cyclopiazonic acid to study the rate of PMCA-mediated reco...
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Spatial and temporal regulation of intracellular Ca(2+) is a key event in many signaling pathways. Plasma membrane Ca(2+)-ATPases (PMCAs) are major regulators of Ca(2+) homeostasis and bind to PDZ (PSD-95/Dlg/ZO-1) domains via their C termini. Various membrane-associated guanylate kinase family members have been identified as interaction partners of PMCAs. In particular, SAP90/PSD95, PSD93/chap...
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14. Silvius. J . K. & Gagne, J. ( 19x4) Hiochmiistry 23, 324 1-3247 15. Hope, M. J. & Cullis, P. R. (1980) Biochem. Biophys. Res. Cornmiin. 92,846-852 16. Portis, A,, Newton, C., Pangborn, W. & Papahadjopoulos, D. ( 1979) Biochemistry 18, 780-790 17. Jacobson, K. & Papahadjopoulos, D. ( 1975) Biochemisfy 14, 152-lhl 18. Ellens, H.. Siegel, D., Alford. I)., Yeagle, P. L.. Boni, L., Lis. L. J.. Q...
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ژورنال
عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Biomembranes
سال: 1998
ISSN: 0005-2736
DOI: 10.1016/s0005-2736(98)00124-2